satellite dnas การใช้

• Satellite DNA, together with minisatellite and microsatellite DNA, constitute the tandem repeats.
• His PhD was on Satellite DNA at the Medical Research Council Unit, in Edinburgh.
• Both the human region and the homologous chimpanzee region are encompassed by typical alpha-satellite DNA found near the chromosome centromeres.
• SpcDNAs are derived from repetitive sequences such as satellite DNA, retrovirus-like DNA elements, and transposable elements in the genome.
• ""'Alphasatellites " "'are single stranded satellite DNA that are dependent on a virus for transmission.
• Nearly all eukaryotic organisms, apart from budding yeasts ( " Saccharomyces cerevisiae " ) have satellite DNA in their normal centromeres.
• Modern phylogenetics uses sophisticated techniques such as alloenzymes, satellite DNA and other molecular markers to describe traits that are shared between distantly related lineages.
• The supernumeraries, which have a satellite DNA, occur in warm, dry environments, and are scarce or absent in humid, cooler localities.
• Hypomethylation of cytosine in centromeric and pericentromeric areas and higher-order repeats of satellite DNA in centromeric DNA can result in such chromosomal loss events.
• Classical satellite DNA is normally heavily methylated at cytosine residues but may become almost fully unmethylated due to ICF syndrome ( Immunodeficiency, centromere instability, and facial anomalies syndrome ) or after treatment by DNA methyl transferase inhibitors.
• The term satellite DNA originates from the observation in the 1960s of a fraction of sheared DNA that showed a distinct buoyant density, detectable as a  satellite peak in density gradient centrifugation, and that was subsequently identified as large centromeric tandem repeats.
• The DNA binding domain recognizes and binds a 17-bp sequence ( CENP-B box ) in the centromeric alpha satellite DNA . This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes.
• Centric heterochromatin is usually formed on alpha satellite DNA in humans; however, there have been cases where centric heterochromatin and centromeres have formed on originally euchromatin domains lacking alpha satellite DNA; this usually happens as a result of a chromosome breakage event and the formed centromere is called a " neocentromere ".
• Centric heterochromatin is usually formed on alpha satellite DNA in humans; however, there have been cases where centric heterochromatin and centromeres have formed on originally euchromatin domains lacking alpha satellite DNA; this usually happens as a result of a chromosome breakage event and the formed centromere is called a " neocentromere ".
• The name " satellite DNA " refers to how repetitions of a short DNA sequence tend to produce a different frequency of the bases adenine, cytosine, guanine and thymine, and thus have a different density from bulk DNA-such that they form a second or'satellite'band when genomic DNA is separated on a density gradient.
• The deepest layer in the kinetochore is the "'inner plate "', which is organized on a chromatin structure containing nucleosomes presenting a specialized histone ( named CENP-A, which substitutes histone H3 in this region ), auxiliary proteins and DNA . DNA organization in the centromere ( satellite DNA ) is one of the least known aspects in vertebrate kinetochores.